Work

The thrombopoietin receptor S264F mutant drives MPN with marrow fibrosis through a dual mechanism

Year: 2026

Type: article

Source: HemaSphere

DOI: 10.1002/hem3.70437

Authors: Charlotte Lees, Emile Brandt, Emmanuel Dutranoix, Gabriel Levy, Bogdan I. Iorga, Hosuk Ryou, Jens Rittscher, Daniel Royston, Stefan N. Constantinescu, Adam J. Mead

Institutions: University of Oxford, NIHR Oxford Biomedical Research Centre, MRC Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit, Ludwig Cancer Research, de Duve Institute, UCLouvain, Centre National de la Recherche Scientifique, Institut de Chimie des Substances Naturelles, Université Paris-Saclay, Ludwig Cancer Research, Oxford University Hospitals NHS Trust, Walloon Excellence in Lifesciences and Biotechnology

Language: English

Topic: Myeloproliferative Neoplasms: Diagnosis and Treatment

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,480

Funders: Ludwig Institute for Cancer Research, Cancer Research UK, National Institute for Health and Care Research, Department of Health and Social Care, Fonds De La Recherche Scientifique - FNRS, Walloon excellence in life sciences and biotechnology, National Institutes of Health, Medical Research Council, Biomedical Research Council, NIHR Oxford Biomedical Research Centre, Health Data Research UK

Awards: G1026935893, Clinical utility and biological impact of platelet-restricted clonal haematopoiesis, G3140501412, G4240373554, G6490342299, G7423961978, G781246347

OpenAlex ID: W7220849672

FWCI:

Cites: 14

Cited by:

Related to: 10