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A Quick-Start Guide to Flux Balance Analysis

Type: article

Abstract: Flux Balance Analysis is commonly used for genome-scale metabolic modelling. It is a constraint-based method that uses linear programming to find the optimal reaction fluxes that satisfy a set of constraints given an objective function. Here I describe the basic steps for conducting Flux Balance Analysis, which is applicable to metabolic networks of any size. I also provide information on general resources for getting started on this method, as well as some practical tips for avoiding or handling common issues.

Source: University of Birmingham Research Portal (University of Birmingham)

Author: Chew, Yin Hoon; id_orcid 0000-0002-9258-583X

Language: English

Topic: Microbial Metabolic Engineering and Bioproduction

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W7220888531

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