Work

Sentinel lymph node-guided modification of postoperative radiotherapy in oral tongue squamous cell carcinoma: a retrospective dosimetric and NTCP modelling study

Year: 2026

Type: article

Abstract: •SLNB identified lymphatic drainage beyond standard elective volumes in nearly half of OTSCC patients.•SLNB may guide individualized postoperative radiotherapy, including omission of contralateral neck irradiation in selected patients.•Adapted plans significantly reduced estimated NTCPs for xerostomia and dysphagia.•SLNB may support individualized de-escalation and optimization of elective neck irradiation in OTSCC.

Source: Clinical and Translational Radiation Oncology

DOI: 10.1016/j.ctro.2026.101306