Work

Synthesis, characterization, X-ray diffraction, in silico studies and in vitro biological evaluation of acylthiourea-derived thiazole-2-imines

Year: 2026

Type: article

Abstract: A series of thiazole-2-imines (1a–1f) with unsubstituted aryl groups or aryl groups bearing methyl, methoxy, fluoro, or nitro substituents was designed using selected structural features of thiamine as inspiration.

Source: RSC Advances

DOI: 10.1039/d6ra07024h

Authors: Edmore F. Kangara, Thishana Singh, Phindile Khoza, Darian Naidu, Nompumelelo P. Mkwananzi, Sibusiso Senzani, Oluwatoba E. Oyeneyin, Manuel A. Fernandes, Werner Van Zyl, Matshawandile Tukulula

Institutions: University of the Witwatersrand, University of KwaZulu-Natal, Walter Sisulu University

Language: English

Topic: Heterocyclic Compound Synthesis and Bioactivity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,042

Funders: National Research Foundation, Inyuvesi Yakwazulu-Natali, Center for High Performance Computing

Award: G6716568004

OpenAlex ID: W7221019770

FWCI:

Cites: 52

Cited by:

Related to: 10