Work

Synthesis of 5-[3-amino-imidazo[1,2- a ]pyridin-6-yl]pyridin-2-ones and derivatives through the combination of palladium-catalyzed cross-coupling and GBB multi-component reactions

Year: 2026

Type: article

Abstract: A combined Suzuki-type palladium-catalyzed cross-coupling and Groebke–Blackburn–Bienaymé (GBB) multicomponent strategy enabled the synthesis of novel 5-[3-amino-imidazo[1,2- a ]pyridin-6-yl]pyridin-2-ones and 3,5-disubstituted pyridin-2-ones.

Source: RSC Advances

DOI: 10.1039/d6ra03865d

Authors: Emma Caillet, Quentin Chevrier, Pascal Retailleau, Sabine Berteina-Raboin, Isabelle Gillaizeau

Institutions: Université d'Orléans, Centre National de la Recherche Scientifique, Institut de Chimie Organique et Analytique, Institut de Chimie des Substances Naturelles, Université Paris-Saclay

Language: English

Topic: Multicomponent Synthesis of Heterocycles

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,042

OpenAlex ID: W7221029164