Year: 2026
Type: article
Abstract: . The possible mechanism includes the shielding effect of Vit. B1 through several non-covalent interactions with insulin. Vit. B6 did not exhibit sufficient insulin amyloid inhibitory activity, even though it maintained the alpha-helical form to some extent during thermal aggregation, unlike Vit. B1. Vit. B12, having a bulkier structure, could not interact with insulin in a stable manner and consequently disrupted the solvated state of insulin.
Source: RSC Advances
DOI: 10.1039/d6ra06247d
Institutions: Jadavpur University, Lady Brabourne College
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,042
OpenAlex ID: W7221049997