Glycosidase-catalysed synthesis of alpha-galactosyl epitopes important in xenotransplantation and toxin binding using the alpha-galactosidase from Penicillium multicolor
Year: 2026
Type: article
Abstract: The alpha-galactosidase from Penicillium multicolor catalyses highly regioselective galactosyl transfer on to mono- and di-saccharide acceptors that have a non-reducing terminal galactose unit to give products containing the alpha-D-Galp-(1 --> 3)-D-Galp epitope found on pig tissue and which is responsible for the hyperacute rejection response in xenotransplantation of pig organs into man.
Source: University of Warwick
Author: No author provided
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W7221086015