Year: 2026
Type: preprint
Abstract: Cell type designations label uniquely-identifiable groups of related cells that typically function in similar ways. Cell types divide the Drosophila melanogaster central nervous system into functional units, but remain challenging to target and identify. Previously we generated a driver line and image resource for targeting many neuron types ( Meissner et al., 2025 ). Here we improve on identifying the targeted neurons by automated searching against electron microscopy datasets and manual scoring of search results to add 6,368 annotations across 1,772 driver lines in the collection. These annotations provide a potential training resource for future search algorithms. We then estimate the number of cell types and thus the fraction of the central nervous system labeled by the collection as a whole.
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7221103780