Work

Implementing modular design principles for molecular homogeneous catalyst discovery

Year: 2026

Type: review

Abstract: Optimising the structure of molecular homogeneous catalysts is essential to ensure they perform as desired. This can be particularly challenging when seeking to realise selectivity in a catalytic process. The modular design strategy provides a powerful approach for evaluating catalyst structure by generating large and diverse libraries of catalysts. Evaluating these catalyst libraries gives invaluable insights into catalyst function and informs the development of more efficient catalysts. In this perspective, we look at various strategies that have been used to implement modular designs to develop new ligands, organocatalysts and photocatalysts.

Source: Catalysis Science & Technology

DOI: 10.1039/d6cy00980h

Authors: Francis Millward, Benjamin S. Grills, Elizabeth M. Dauncey, Kenneth F. Clark, Benjamin N. Bhawal

Institutions: University of Edinburgh, AstraZeneca (United Kingdom)

Language: English

Topic: Organometallic Complex Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Funders: Royal Society, University of Edinburgh, Engineering and Physical Sciences Research Council

OpenAlex ID: W7221124622