Glycosidase-catalysed synthesis of oligosaccharides: A one step synthesis of lactosamine and of the linear B type 2 trisaccharide alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAcSEt involved in the hyperacute rejection response in xenotransplantation from pigs to man and as the specific receptor for toxin A from Clostridium difficile
Year: 2026
Type: article
Abstract: Sequential use of the beta-galactosidase from Bacillus circulans and an a-galactosidase from Aspergillus oryzae give the linear B trisaccharide 2, identified as the epitope that binds anti-Gal antibodies during pig-to-man xenotransplantation and as the receptor for toxin A from Clostridium difficile.
Source: University of Warwick
Author: No author provided
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W7221180048