Glycosidase-catalysed synthesis of oligosaccharides: Trisaccharides with the alpha-D-Gal-(1->3)-D-Gal terminus responsible for the hyperacute rejection response in cross-species transplant rejection from pigs to man
Year: 2026
Type: article
Abstract: alpha-Galactosidases from Coffea arabica, Aspergillus niger and A. oryzae catalyse the transfer of alpha-galactosyl residues on to lactose thioglycosides to give 1 --> 3 and 1 --> 6 linked trisaccharides, including an unusual branched trisaccharide 11 and the isoglobotriose glycoside 4, which, as 'linear B type 6', has been recognised as of the type responsible for the hyperacute rejection response in pig-to-man xenotransplantation.
Source: University of Warwick
Author: No author provided
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W7221195925