Cognitive Eloquence During Awake Glioma Surgery: Connectome Representation and Anatomical White-Matter Control Analysis Code
Year: 2026
Type: software
Abstract: This repository contains the analysis code and selected derived data supporting the manuscript "Pathway Identity Versus Disconnection Burden in Higher Cognitive Eloquence During Awake Glioma Surgery: Connectome Representation Scales and Anatomical White-Matter Controls."The study compares structural-connectome representations of 72 published subcortical direct electrical stimulation (DES) sites associated with Spatial perception (n=26) and Mentalizing (n=46).The analyses evaluate anatomical coordinates, 24 major pathway families, total streamline-disconnection burden, and graph-based measures of network consequence.The 24-family representation achieved an out-of-fold AUROC of 0.799, compared with 0.702 for coordinates. The paired difference was not statistically established.An additional anatomical control analysis compared 41 tissue-dominant DES sites with matched white-matter locations. No significant difference in global network-efficiency loss was identified.The repository includes Python analysis scripts, derived results, sensitivity analyses, matching outputs, and reproducibility documentation.External normative tractography and neuroimaging atlases are not redistributed. Full reconstruction requires the upstream datasets and adaptation of historical analysis paths.Version: 1.0.0DOI: 10.6084/m9.figshare.34350843
Source: Figshare
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7221525131