Imaging features of synchronous bilateral primary tumors of oncocytic thyroid carcinoma and papillary thyroid carcinoma: A case report
Year: 2026
Type: article
Study design: Case Report
Abstract: BACKGROUND: Oncocytic thyroid carcinoma (OTC), previously known as Hürthle cell carcinoma, is a distinct subtype of differentiated thyroid cancer accounting for approximately 5% of all thyroid malignancies. Synchronous thyroid tumors are extremely rare, accounting < 1% of all thyroid tumors. CASE SUMMARY: We report a 38-year-old female with synchronous OTC in the left lobe and papillary thyroid carcinoma (PTC) in the right lobe, who had a history of thyroid nodules for 8 years. Ultrasound showed that the OTC was a large, hypoechoic, solid nodule with regular margins and internal vascularity. Contrast-enhanced computed tomography confirmed a heterogeneous, well-circumscribed enhancing mass extruding the thyroid boundary, with no cervical lymph node enlargement in the left lateral compartment. The right-lobe PTC was an ill-circumscribed node with spot calcification and internal nonuniform enhancement. It was smaller than the left-lobe OTC, and enlarged lymph nodes in the right lateral cervical compartment were identified. The patient underwent total thyroidectomy. Histopathology confirmed the diagnosis of synchronous minimally invasive left-lobe OTC right-lobe PTC, with right lateral neck compartment lymph node metastasis. CONCLUSION: This case highlights the importance of recognizing imaging features of coexisting PTC and OTC for preoperative evaluation and surgical management.
Source: World Journal of Radiology
DOI: 10.4329/wjr.126932
Authors: Qi-Shu Gong, Xiao-Wen Liu, Xun-Peng Luo, Nan Xu
Institution: ShenZhen People’s Hospital
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7221552229