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Perioperative and early oncologic outcomes of complex segmentectomy via uniportal video-assisted thoracic surgery for primary lung cancer

Year: 2026
Type: article
Abstract: Background: Uniportal video-assisted thoracic surgery (U-VATS) has been increasingly adopted. However, evidence regarding the safety and oncologic outcomes of U-VATS complex segmentectomy remains limited. We aimed to evaluate the perioperative and early oncologic outcomes of U-VATS complex segmentectomy for primary lung cancer. Methods: We retrospectively reviewed patients who underwent U-VATS complex segmentectomy for primary lung cancer at our institution between December 2021 and November 2025. Patient characteristics, perioperative outcomes, and oncologic outcomes were evaluated. Results: Eighty-two patients were enrolled. The median age of the patients was 72 years. The indication for segmentectomy was intentional in 61 patients (74.4%) and compromised in 21 patients (25.6%). The median operative time was 152 min and the median estimated blood loss was 6 mL. Conversion was required in 3 patients (3.7%). All conversions were performed in a controlled manner; no patients required emergency thoracotomy. Postoperative complications occurred in 4 patients (4.9%). There were no 30- or 90-day mortalities or readmissions within 30 days after surgery. R0 resection was achieved in all patients. The median follow-up duration was 10 months. No local recurrence was observed during the follow-up period. Distant recurrence occurred in 4 patients (4.9%). Conclusions: U-VATS complex segmentectomy for primary lung cancer was associated with postoperative complication and conversion rates consistent with those reported for other thoracoscopic approaches. These findings support the technical feasibility of U-VATS complex segmentectomy in appropriately selected patients when performed with meticulous preoperative planning and standardized intraoperative strategies.
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W7221748374
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