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Phytotoxicity and Data Analytics Pipeline for Silver-Coated Cobalt Ferrite Nanoparticles (Ag@CoFe2O4 NPs) in Wheat Plants

Year: 2026

Type: article

Abstract: This notebook implements an advanced ecotoxicological data analytics pipeline to evaluate the phytotoxicity and multivariate physiological impacts of silver-coated cobalt ferrite nanoparticles (Ag@CoFe2O4 NPs) in wheat plants. Organized into four analytical stages, the workflow handles ICP-OES elemental profiling with limit-of-detection (LOD) corrections to quantify bioaccumulation across separate vegetative compartments (shoot vs. root). It establishes critical environmental thresholds using a many-to-one Dunnett's post-hoc test (isolating NOAEC and LOAEC values) and derives conservative, purely toxicological indices (IC50) via a non-linear 3-parameter log-logistic model (LL.3). Finally, the framework employs Z-score standardization and Principal Component Analysis (PCA) biplots to decode the coupled relationships between intracellular metal burdens, photosynthetic pigments, and the protective antioxidant enzymatic machinery (CAT, APX, GPX, SOD).

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.23377917

Authors: López-Luna, J., Cruz-Fernández, S., Vázquez-Hipólito, V., Martinez-Vargas, S., Martínez I., A., Mijangos-Ricardez, O.F., Solís-Domínguez, F.A., Cuevas-Díaz, M.C.

Institutions: Universidad de la Sierra Juárez, Technological University of the Mixteca, Universidad Autónoma del Carmen, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Universidad Autónoma de Baja California, Universidad Veracruzana

Language: English

Topic: Nanoparticles: synthesis and applications

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Zero hunger

Open Access status: green

OpenAlex ID: W7221748596

FWCI:

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