Work

Untangling the Molecular Mechanism of SpCas9 HNH Domain Checkpoint Activation: A Gear-and-Wedge Fitting Model

Year: 2026

Type: article

Source: ACS Catalysis

DOI: 10.1021/acscatal.6c05718

Authors: Xinyi Li, Jiacheng Wei, Feiying Chen, Jianxiang Huang, Mingyu Li, Ning Liu, Jian Zhang, Shaoyong Lu

Institutions: Shanghai Jiao Tong University, Ningxia Medical University

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funder: National Science and Technology Major Project

Award: G3145871626

OpenAlex ID: W7221761608

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Cites: 67

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