Work

Calculation of Mass Balance Chemical Stressed Active Pharmaceutical Ingredients by Example of Oxidized Nicotinamide Dinucleotide

Year: 2026

Type: article

Abstract: A mass balance calculation for active pharmaceutical substances subjected to chemical stress was performed using oxidized nicotinamide adenine dinucleotide (NAD+) as an example. Calculations were carried out for low, moderate, and extensive degradation of NAD+ induced by basic hydrolysis. The applicability of using the mass balance as a criterion for the reliability of an analytical method is discussed.

Source: Scholars Academic Journal of Pharmacy

DOI: 10.36347/sajp.2026.v15i10.003

Author: Stanislav V. Yefimov

Language: English

Topic: Analytical Methods in Pharmaceuticals

Subfield: Analytical Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

OpenAlex ID: W7221762693

FWCI:

Cites: 4

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Related to: 10