Work

Discovery of Tricyclic Oxazinoquinolinone-Based BCL6 PROTAC Degraders with Potent Activity Against Diffuse Large B-Cell Lymphoma

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c02040

Authors: Xuetao Chen, Rujun Xu, Xiaoran Wang, Huidan Wu, Nan Wang, Xin Huang, Wenjing Kang, Qidong You, Xiaoke Guo, Zhengyu Jiang

Institutions: China Pharmaceutical University, Hunan University

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: Fundamental Research Funds for the Central Universities

Awards: G2490947254, G6187033865

OpenAlex ID: W7221762985

FWCI:

Cites: 48

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