Work

Issues in the Electrochemical Dehydrogenation of Secondary Amines

Year: 2026

Type: article

Abstract: Herein, we report mechanistic studies on the ruthenium-catalyzed dehydrogenation of secondary amines using 2,6-dimethoxybenzoquinone as an electrochemically regenerable mediator. The Shvo catalyst [(C5Ph4O)RuH]2 operates at 90 °C at a potential of +0.4 V to dehydrogenate the amine to the imine at the anode. Hydrogen gas is generated at the cathode. Issues such as protonation of the amine are identified and circumvented by using lutidine as a proton-transfer base.

Source: Organometallics

DOI: 10.1021/acs.organomet.6c00278

Authors: Ignacio Camarero Temiño, Mikhaila D. Ritz, William D. Jones

Institution: University of Rochester

Language: English

Topic: Asymmetric Hydrogenation and Catalysis

Subfield: Inorganic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,500

Funders: National Science Foundation, Chemical Sciences, Geosciences, and Biosciences Division