Work

Engineering catalytic promiscuity in serum albumin: synergistic roles of microenvironment, structural dynamics, and nano conjugation

Year: 2026

Type: article

Abstract: BSA exhibits intrinsic esterase-like promiscuity toward PNPA, governed by a histidine-centered catalytic microenvironment, substrate hydrophobicity, pH and ionic strength. PEGylation suppresses, whereas AuNP conjugation enhances, catalytic activity.

Source: RSC Advances

DOI: 10.1039/d6ra02723g

Authors: Swapan Patra, Nilanjan Dey

Institution: Birla Institute of Technology and Science, Pilani

Language: English

Topic: Protein Interaction Studies and Fluorescence Analysis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $1,042

OpenAlex ID: W7221798076

FWCI:

Cites: 46

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Related to: 10