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Neuroendocrine Disorders of the Epithelial Barrier and Motor Function of the Digestive System in an Adrenalectomy Model

Year: 2026

Type: article

Abstract: The article examines the endocrine, hemodynamic, and metabolic mechanisms that may affect the structural and functional state of the digestive tract under conditions of adrenalectomy. Adrenal hormones participate in the regulation of energy metabolism, water-electrolyte homeostasis, and vascular reactivity. Therefore, their deficiency may affect the perfusion of gastric and intestinal tissues, the renewal of epithelial cells, and the protective properties of the mucous membrane. When assessing possible changes in the digestive system, it is important to study histological structure, microcirculation, motility, and secretory activity in an interrelated manner. The adrenalectomy model makes it possible to experimentally investigate the functional relationships between endocrine regulation and the digestive organs.

Source: HSR (London)

DOI: 10.5281/zenodo.23374008

Authors: Madazizova Dilfuza Rahmatullaevna, Usanova Saodat Turaevna, Safarova Sanobar Omontoshevna, Worldly Knowledge Publishing Centre

Institutions: Westminster International University in Tashkent, National Pedagogical University of Uzbekistan named after Nizami, National University of Uzbekistan

Language: English

Topic: Adrenal Hormones and Disorders

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7221801149

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