Year: 2026
Type: preprint
Abstract: We report a mechanochemical copper-catalyzed defluorosilylation of α-trifluoromethyl styrenes with silylboranes. Mechanical activation dramatically accelerated the C–F bond transformation, reducing the reaction time from 8 h to only 30 min at room temperature while substantially decreasing solvent consumption. The reaction exhibits broad substrate compatibility and scalability, highlighting mechanochemistry as an effective strategy for accelerating selective C–F bond functionalization.
Source: ChemRxiv
Institution: Nagoya Institute of Technology
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
Awards: G1268994732, フッ素循環社会を実現するフッ素材料の精密分解
OpenAlex ID: W7222003319