Work

Urinary biomarkers in non-muscle invasive bladder cancer: translating multiplex and genomic liquid biopsies into clinical practice

Year: 2026

Type: article

Abstract: Urinary biomarkers have long promised to reduce the cystoscopy burden in bladder cancer, but a persistent gap separates assay performance from clinical practice. This review synthesizes the shift from protein-based tests to multiplex, genomic, and extracellular-vesicle liquid biopsies, including minimal residual disease detection and therapy selection, and sets out an implementation roadmap spanning pre-analytical standardization, decision thresholds, and pragmatic trial design.

Source: npj Precision Oncology

DOI: 10.1038/s41698-026-01723-4