Ten simple rules to build genomics capacity for routine laboratory practice in the Global South
Year: 2026
Type: article
Abstract: Developing sustainable genomics capacity in the Global South requires more than technology transfer; it depends on human-centered approaches based on the workflows and existing expertise of laboratory personnel, institutional collaboration, and long-term integration into health systems. Drawing on lessons learned from regional capacity-building initiatives, this article proposes ten simple rules for implementing and sustaining genomics capacity within public health and clinical laboratory settings. These rules emphasize local context, strategic planning, continuous learning, and equitable collaboration. Together, they provide a roadmap for laboratories aiming to transform genomic technologies from research tools for diagnosis, surveillance and decision-making, into routine instruments for public health in low- and middle-income countries.
Source: PLoS Computational Biology
Authors: Emilyn Costa Conceição, Abhinav Sharma, Davi Josué Marcon, Layana Rufino Ribeiro, Danna Karen Corrêa dos Santos, Lilian Eduarda de Oliveira Freitas, Alex Brito Souza, Hendor Neves Ribeiro de Jesus, Maria Cristina da Silva Lourenço, Valnete das Graças Dantas Andrade, Marco Aurélio Almeida de Oliveira, Tatyana Costa Amorim Ramos, Ítalo José Mesquita Cavalcante, Arabela Leal e Silva de Melo, Nabila Ismail, Tulio de Oliveira, Robin Mark Warren, Adriana Ayden Ferreira, Theolis Costa Barbosa Bessa, Cristiane Cunha Frota, Philip Noel Suffys, Karla Valéria Batista Lima
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,043
Funder: Universiteit Stellenbosch
OpenAlex ID: W7222236367