Work

Case Report: Electroencephalography-informed low-frequency repetitive transcranial magnetic stimulation targeting the supplementary motor area in severe functional movement disorder

Year: 2026

Type: article

Abstract: Background: Functional movement disorder (FMD) is increasingly being recognized as a condition associated with abnormal brain network connectivity; however, effective treatment strategies remain limited. Methods: We report the case of a patient with severe FMD that developed following an occupational injury and was characterized by functional tremors accompanied by migraines and prominent autonomic symptoms. Based on electroencephalography (EEG) network analysis, low-frequency repetitive transcranial magnetic stimulation targeting the supplementary motor area was administered, followed by staged rehabilitation incorporating visual feedback. Results: The combined intervention reduced tremors and improved gait speed, activities of daily living, and EEG network connectivity. Conclusion: This case highlights the potential utility of combining EEG-guided neuromodulation with staged rehabilitation for the treatment of FMD and supports further investigation of this approach.

Source: Frontiers in Psychiatry

DOI: 10.3389/fpsyt.2026.1959751

Authors: Chiaki Takahashi, Takashi Asahi, Motoki Kanda, Yoshihiko Ohta, Isao Matsushita

Institutions: Kanazawa Medical University, Kanazawa Hospital, Kanazawa Medical University Hospital

Language: English

Topic: Transcranial Magnetic Stimulation Studies

Subfield: Neurology

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801