Work

Case Report: 18F-FDG PET/CT findings and SUVmax characterization in a dog with apocrine gland anal sac adenocarcinoma

Year: 2026

Type: article

Abstract: Apocrine gland anal sac adenocarcinoma (AGASACA) is a malignant epithelial tumor in dogs that commonly metastasizes to regional lymph nodes. Although 18 F-fluorodeoxyglucose ( 18 F-FDG) positron emission tomography/computed tomography (PET/CT) has been mentioned as a staging modality for this tumor, detailed imaging findings and maximum standardized uptake values (SUVmax) have not previously been reported. A 10-year-old castrated male Maltese was referred for a right anal sac mass and suspected lymph node metastasis. Preoperative 18 F-FDG PET/CT revealed increased uptake in the primary mass (SUVmax 7.3), the internal iliac lymph node (SUVmax 6.35), and the lumbar aortic lymph node (SUVmax 4.3), with no evidence of distant metastasis. Therefore, the dog was therefore classified as Stage IIIa. Based on these findings, intra-abdominal lymphadenectomy and right anal sacculectomy were performed. Histopathology confirmed AGASACA in the primary mass and morphologically similar metastatic adenocarcinoma in the resected lymph nodes. To our knowledge, this is the first report of 18 F-FDG PET/CT findings and SUVmax values in a dog with AGASACA and histologically confirmed lymph node metastases. These findings suggest that PET/CT may provide complementary metabolic information for preoperative nodal staging.

Source: Frontiers in Veterinary Science

DOI: 10.3389/fvets.2026.1977879

Authors: Bohyeon Shim, Yujin Kim, Sungin Lee

Institution: Chungbuk National University

Language: English

Topic: Veterinary Oncology Research

Subfield: Small Animals

Field: Veterinary

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801