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Anterior Segment Ischemia and Neurotrophic Keratopathy Following Ultrasound Cycloplasty in Acute Angle-Closure Glaucoma

Year: 2026

Type: article

Abstract: Ultrasound cycloplasty (UCP) is a minimally invasive, non-incisional glaucoma procedure that has emerged in recent years and is generally associated with few complications. We report a case of a patient with acute angle-closure glaucoma underwent UCP for IOP control. She developed iris neovascularization and neurotrophic keratopathy（NK）at postoperative week 6, followed by hypopyon, flattening of the anterior chamber, and thinning of the peripheral cornea at postoperative week 11, 12, and 14, respectively. We concluded that UCP can lead to anterior segment ischemia (ASI) and NK, which manifest as iris neovascularization, painless corneal epithelial defects, peripheral corneal thinning, hypopyon, and flattening of the anterior chamber. Preoperative screening for high-risk factors is essential before performing UCP.

Source: Journal of Glaucoma

DOI: 10.1097/ijg.0000000000002779

Authors: Xiangyun Kong, Mugen Liu, Fei Luo, Xusheng Cao, Shan Song, Yiying Li, Han Zhang, Chunyan Qiao

Institutions: Shandong Provincial Hospital, Shandong First Medical University, Southwestern Medical Center, The University of Texas Southwestern Medical Center, Beijing Tongren Hospital, Capital Medical University

Language: English

Topic: Glaucoma and retinal disorders

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7222702575

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