Work

Comparative biochemical analysis of tea ( Camellia sinensis ) and coffee ( Coffea arabica ) extracts identifies the ethyl acetate fraction of green tea as a potential dual digestive enzyme inhibitor: an in vitro and in silico study

Year: 2026

Type: article

Abstract: in a preliminary cytotoxicity screen. Molecular docking was consistent with the experimental findings, suggesting that hesperidin and rutin may contribute to competitive α-amylase inhibition and allosteric pancreatic lipase modulation. These findings indicate that the ethyl acetate fraction of green tea is a phenolic-rich fraction with dual digestive enzyme inhibitory activity that merits further evaluation in appropriate biological models.

Source: RSC Advances

DOI: 10.1039/d6ra07857e

Authors: Youmna E. El-Saied, Abdullah A. Elgazar, Fardous F. El-Senduny, Nada E. Hammouda, Omali Y. El-Khawaga, Farid A. Badria

Institutions: Mansoura University, Kafrelsheikh University

Language: English

Topic: Tea Polyphenols and Effects

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $1,042

Funder: Mansoura University