Work

A Key Biomarker lnc-ABCA12-5:2 Compensating Diagnostic Deficiencies for Indeterminate Thyroid Nodules and Genetically Wild-Type Thyroid Malignancies

Year: 2026

Type: article

Abstract: lnc-ABCA12-5:2 and lnc-MPEG1-1:1 are robust preoperative biomarkers for PTC. lnc-ABCA12-5:2 fills critical diagnostic gaps in indeterminate and genetically wild-type thyroid malignancies, and correlates with aggressive tumor molecular profiles, underscoring its translational potential for clinical risk stratification.

Source: Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics

DOI: 10.32604/or.2026.088872

Authors: Xuan Su, Wen-na Xu, Bu Zou, Chan Huang, Cai-yun He, Zu-lu Ye

Institutions: Sun Yat-sen University, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Sixth Affiliated Hospital of Sun Yat-sen University

Language: English

Topic: Thyroid Cancer Diagnosis and Treatment

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: Basic and Applied Basic Research Foundation of Guangdong Province