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Electrosynthesis of 1 H - and 2 H -indazoles by reduction of o -nitrobenzylamines, a versatile and sustainable access

Year: 2026

Type: article

Abstract: An efficient, simple, and sustainable electrochemical transformation of o -nitrobenzylamines to their respective indazoles has been developed, showing broad functional group tolerance, scalability, post-functionalization and access to API precursors.

Source: Organic Chemistry Frontiers

DOI: 10.1039/d6qo01360k

Authors: Eric F. R. Pertermann, Daniel Doellerer, Claudia M. Kammler, Thomas Weyhermüller, Sebastian B. Beil, Bernd Werner, Siegfried R. Waldvogel

Institutions: Max Planck Institute for Chemical Energy Conversion, Boehringer Ingelheim (Germany), Karlsruhe Institute of Technology

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Funders: Deutsche Forschungsgemeinschaft, Fraunhofer-Gesellschaft, Max-Planck-Gesellschaft

OpenAlex ID: W7222965676

FWCI:

Cites: 65

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Related to: 10