Work

A focus on caging radicals: a catch-and-release mechanism for BODIPY photocages

Year: 2026

Type: article

Abstract: , 11430, https://doi.org/10.1039/D6SC01848C) show how homolytic bond scission can instead be used to achieve a catch-and-release mechanism for radical payloads. Using a BODIPY-based photocage that responds to green light (525 nm), they demonstrate the capture of TEMPO and its subsequent release on demand. This behaviour was also applied to radical-based polymerisation. This work establishes design principles for the catch-and-release mechanism, and draws attention back to the often overlooked homolytic pathway in photocage chemistry.

Source: Chemical Science

DOI: 10.1039/d6sc90197b

Authors: Jiarong Wu, Jake L. Greenfield

Institution: University of St Andrews

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: Royal Society of Chemistry, European Commission, Deutsche Forschungsgemeinschaft

Awards: G7074808140, G9000841451