Work

Construction of multifunctional cerium-containing nanozyme hydrogel and its component-level functions in skin wound healing

Year: 2026

Type: article

Abstract: ) growth. It also promotes the polarization of macrophages from a pro-inflammatory (M1) to a pro-healing (M2) phenotype and enhances fibroblast proliferation. In a mouse full-thickness skin defect model, application of the hydrogel promotes wound closure, reduces scarring, and promotes complete epidermal regeneration. Histological analysis reveals decreased inflammatory infiltration and dense, organized collagen deposition resembling healthy skin. This multifunctional dressing integrates antioxidant, anti-inflammatory, and antibacterial activities, providing a proof-of-concept strategy for acute cutaneous wound repair.

Source: RSC Advances

DOI: 10.1039/d6ra05052b

Authors: Xin Bao, Qiyao Tang, Chen Dong, Mingsheng Xu, Xiao Xu

Institutions: Yixing People's Hospital, Ningbo University, Ningbo University of Finance & Economics, Chinese Academy of Sciences, Suzhou Institute of Nano-tech and Nano-bionics

Language: English

Topic: Wound Healing and Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042