Work

COX-2-engineered bone marrow mesenchymal stromal cells prolong skin allograft survival after scald injury by shifting the Treg/Th17 balance

Year: 2026

Type: conference-paper

Abstract: Objectives and questions: Allogeneic skin coverage is often required after extensive burns/trauma when donor sites are limited, but immune rejection shortens graft survival. BMSCs are immunomodulatory yet may be insufficient at standard dosing. COX-2 enhances PGE2 production and supports Treg-mediated [for full text, please go to the a.m. URL]

Source: German Medical Science (German Research Foundation)

DOI: 10.3205/26dkou344

Author: Xu, Chengfeng

Institution: Chinese PLA General Hospital

Language: English

Topic: Mesenchymal stem cell research

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7223009240

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