Work

1,2,3-Triazolyl indole-piperazine hybrids as potential anti-tubercular agents: design, synthesis, in vitro , and in silico evaluation

Year: 2026

Type: article

Abstract: studies identified three promising lead molecules (R11, R13 and R15) with significant antitubercular activity and emphasizing the importance of the 1,2,3-triazolyl indole-piperazine scaffold for the development of next-generation anti-TB therapeutics.

Source: RSC Advances

DOI: 10.1039/d6ra05893k

Authors: Rajkumar Reddyrajula, Umadevi Etikyala, Mohammed Muzaffar-Ur-Rehman, Sampat Parayya Vibhutimath, Udayakumar Dalimba, Shreeganesh Subraya Hegde, Chandra Sekhar Kondapalli Venkata Gowri, Vijjulatha Manga

Institutions: Osmania University, Birla Institute of Technology and Science, Pilani, National Institute of Technology Karnataka, Dayananda Sagar University, Birla Institute of Technology and Science - Hyderabad Campus

Language: English

Topic: Synthesis and Characterization of Heterocyclic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042

Funder: Osmania University

OpenAlex ID: W7223060732

FWCI:

Cites: 44

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Related to: 10