Work

Synthesis, crystal structure and Hirshfeld surface analysis of ( E )-5-methoxy-2-[( p -tolylimino)methyl]phenol

Year: 2026

Type: article

Abstract: Single-crystal X-ray diffraction has been used to elucidate the molecular and crystal structures of ( E )-5-methoxy-2-[( p -tolylimino)methyl]phenol {systematic name: ( E )-5-methoxy-2-[ N -(4-methylphenyl)carboximidoyl]phenol}, C 15 H 15 NO 2 . The Schiff base crystallizes in the orthorhombic space group Pca 2 1 and the molecular structure is stabilized by an intramolecular O—H...N hydrogen bond, with an O...N separation of 2.605 (4) Å and an O—H...N angle of 146°. The crystal packing was examined using Hirshfeld surface analysis, which reveals dominant H...H contacts make the largest contribution to the intermolecular contacts (51.4%) of the surface, followed by H...C/C...H (30.9%), H...O/O...H (12.0%) and H...N/N...H (2.5%) contacts. The combined crystallographic and Hirshfeld surface analyses provide insight into the molecular organization and intermolecular forces governing the solid-state structure.

Source: Acta Crystallographica Section E Crystallographic Communications

DOI: 10.1107/s205698902601056x

Authors: G.M. Pradeepalakshmi, Valarmathy Govindaraj, Arumugaperumal Reshmadevi, Subramanian Ramasamy, Elias Jesu Packiam

Institutions: University of Neuchâtel, Bharathidasan University, Seethalakshmi Ramaswami College, SRM Institute of Science and Technology, Indian Institute of Technology Madras

Language: English

Topic: Crystal structures of chemical compounds

Subfield: Inorganic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $500

OpenAlex ID: W7223063181