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Structure-Based Design of 2-(Pyridone)Indoles as Antagonists of the Toll-Like Receptors TLR7 and TLR8 for the Treatment of Autoimmune Disorders

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Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.6c02682
Authors: Dharmpal S. Dodd, John L. Gilmore, Tasir S. Haque, Brian K. Whiteley, Shana L. Posy, Dawn Mulligan, David Critton, Rosemary Zhang, Hongchen Qiu, Mary Ellen Cvijic, Murali Subramanian, Debarati Mazumder Tagore, Shailesh Dudhgaonkar, Mary Harner, Louis J. Lombardo, John E. Macor, Stefan Ruepp, Gary L. Schieven, Alaric J. Dyckman
Institution: Bristol-Myers Squibb (United States)
Language: English

Topic: Immune Response and Inflammation
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W7223094734
FWCI:
Cites: 26
Cited by:
Related to: 10
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