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Parainfectious Urticarial Rash in a Young Female with Epstein-Barr Virus Infection: A Case Report

Year: 2026
Type: article
Study design: Case Report
Abstract: Introduction: Urticarial rash is a common condition but can present atypically, making it difficult to clinically diagnose. Thorough assessment with awareness and exclusion of differentials is crucial for definitive treatment. Case Report: This is a case of a 23-year-old woman who presented with signs and symptoms suggestive of streptococcal pharyngitis and was treated with clarithromycin by primary care. Two weeks later, the patient was referred to the emergency department for malaise and an acute, rapidly progressing pruritic rash. Further evaluation revealed an Epstein-Barr virus (EBV) infection. Conclusion: This case highlights the differential diagnoses and diagnostic reasoning required for a patient with a rash and concurrent respiratory symptoms. Differential considerations include viral exanthem, delayed drug-induced reaction, EBV-associated antibiotic rash, scarlet fever, and urticarial vasculitis. Early identification of atypical urticarial lesions and the exclusion of clinical mimics are vital to guide appropriate therapy and optimize patient outcomes.
Language: English
Subfield: Dermatology
Field: Medicine
Open Access status: gold
Estimated APC paid: $500
OpenAlex ID: W7223101189
FWCI:
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Related to: 10