Work

Giant Duodenal Perforation Secondary to Malaria in a 5‐Year‐Old Girl: Case Report and Review

Year: 2026

Type: article

Abstract: Background Peptic ulcer disease (PUD) is rare in children, with complications like perforation being especially uncommon. Malaria, a major health burden in endemic regions, is associated with severe complications, but giant duodenal perforation as a direct consequence is remarkably rare. This report presents a 5‐year‐old girl with a giant duodenal perforation secondary to malaria, highlighting the need for prompt diagnosis and intervention. Case Presentation A 5‐year‐old girl from a malaria‐endemic area presented with fever, vomiting, and diarrhea. Diagnosed with severe malaria, she developed acute abdominal pain and signs of peritonitis. Imaging confirmed duodenal perforation, which was surgically repaired. Postoperative recovery was successful, and Helicobacter pylori infection was ruled out. Conclusion Giant duodenal perforation can occur as a rare complication of severe malaria in children without typical peptic ulcer risk factors. Early recognition and timely surgical and antimalarial treatment are critical to improving outcomes in malaria‐endemic settings.

Source: Case Reports in Surgery

DOI: 10.1155/cris/5569916

Authors: Ashenafi Shegaw, Mahiderekal Mengistu Berkit, Milki Tufa, Alo Edin

Institution: Bule Hora University

Language: English

Topic: Gastrointestinal Bleeding Diagnosis and Treatment

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $790