Work

An activatable fluorescent probe for fibroblast activation protein α and its bioimaging applications

Year: 2026

Type: article

Abstract: visualization and monitoring of FAP in living cancer cells and tissues were performed using DDAF, indicating the widespread expression of FAP in a variety of tumors. These findings provide a promising tool for discovering potent therapeutic agents targeting FAP and for the real-time visualization and monitoring of FAP in tumors.

Source: RSC Advances

DOI: 10.1039/d6ra05595h

Authors: Lei Feng, Hengjing Chen, Zhenhao Tian, Wenpeng Li, Yifei Dang, Guobiao Liang, Chengjuan Xing, Xiaohong Shu, Jing Ning, Fangyu Yang, Xiaochi Ma

Institutions: Dalian Medical University, Second Affiliated Hospital of Dalian Medical University, Xuzhou Medical College, Northwestern Polytechnical University, General Hospital of Shenyang Military Region

Language: English

Topic: Molecular Sensors and Ion Detection

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042

Funders: Department of Science and Technology of Liaoning Province, Dalian Medical University

Award: G7465794625

OpenAlex ID: W7223158712

FWCI:

Cites: 24

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Related to: 10