Fabrication of a Bimetallic NiFe-Prussian Blue-MoS2 Nano-heterojunction for NIR-Triggered Antibacterial Activity
Year: 2026
Type: preprint
Abstract: Bacterial infections continue to pose a major threat to human health globally, and the rapid emergence of antibiotic-resistant microorganisms has created an urgent need for development of effective non-antibiotic therapeutic strategies for pathogen eradication. In this work, a series of peroxidase-like NiFe-PB@MoS 2 (PB: Prussian Blue) heterostructured nanocomposite (NFPPM) catalysts were successfully synthesised to achieve significantly enhanced antibacterial activity. In the prepared heterostructure, MoS2 nanoflowers were decorated with NiFe-PB nanoparticles through an in situ growth process. The incorporation of NiFe-PB effectively improved the catalytic and photothermal activity of MoS 2 under NIR irradiation. After 10 min of NIR exposure, the NFPPM nanocomposite exhibited remarkable antibacterial efficiency against Staphylococcus aureus Escherichia coli . Peroxidase-like nanozymes have been extensively explored in various biomedical applications because of their excellent catalytic properties. The as-prepared NFPPM demonstrated enhanced peroxidase-like activity, leading to superior antibacterial performance. Furthermore, this work provides a promising strategy based on adhesive nanozymes that can closely interact with bacterial surfaces, offering valuable insight into the design of highly efficient heterojunction-containing photocatalysts with superior antibacterial activity.
Source: ChemRxiv
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W7223218517