Year: 2026
Type: article
Abstract: BACKGROUND: Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy and poses major diagnostic and therapeutic challenges in Latin America, owing to heterogeneity in resource availability, access to advanced technologies, and the organization of health systems. OBJECTIVES: To develop the first Inter-American Consensus on HCM, in order to standardize the care of these patients tailored to the regional context. METHODS: The Inter-American Society of Cardiology (SIAC) convened a committee of experts from different countries across the Americas. A systematic review of the evidence was performed, followed by the development of recommendations, which were validated using a formal Delphi methodology; consensus was defined as agreement among more than 80% of participants. RESULTS: The consensus provides a comprehensive approach to the evaluation and management of HCM. It covers epidemiology, pathophysiology, multimodality diagnostic tools, genetics and family counseling, phenocopies, pharmacological and invasive treatment, associated complications, sudden cardiac death risk assessment, special populations (pediatric and pregnant patients), physical exercise, and follow-up strategies. In addition, it includes specific recommendations aimed at facilitating the implementation of these across Latin America. CONCLUSIONS: The Inter-American Consensus on HCM provides recommendations for the diagnosis and treatment of this condition. It integrates the best available evidence with regional clinical experience and takes into account the epidemiological, economic, and healthcare characteristics of the region. It constitutes a reference framework for standardizing the care of patients with HCM and their families throughout Latin America.
Authors: Carlos E. Rochitte, Manlio F. Márquez-Murillo, Enrique A. Berríos-Bárcenas, Joffre Lara-Terán, Daniel Sierra-Lara-Martínez, Diego X. Chango, Cristhian E. Scatularo, Adrián Baranchuk, Ricardo López-Santi, Ingrid Márquez, Clara Saldarriaga, Jairo A. Rendón-Giraldo, Diego Pérez-de Arenaza, Andrés F. Miranda-Arboleda, Ana Múnera-Echeverri, Sergio Baratta, Víctor Rossel, María I. Sosa-Liprandi, María J. Rodríguez-González, Juan P. Costabel, Ana Berni-Betancourd, Karina González-Carta, Juan D. López-Ponce de León, Fabio Fernandes, Paola A. Morejón-Barragán, Josefina B. Parodi, Carlos Guamán-Valdivieso, Ana C. Alba, Eugenio Cingolani, Luis E. Gómez, Ricardo Stein, Roberto Concepción- Chacón, Gabriel Parma-Romanelli, Susana Blanco-Sobrino, Franco Leoni, Jorge Jalil, Yamiris Delgado, Liliana Posada-Martínez, Landy Rodríguez-Amaguay, Víctor Arévalos, Florencia B. Cantora, Mariano D. Estofán, Ivonne Cárdenas-Reyes, Noël Brögger, María C. Bejarano, Ignacio Vaca-Valverde, Carlos Olivares-Asencio, Leandro Cura-Hochbaum, Agostina M. Fava, Eric Karabut, María M. Sáenz-Tejeira, Katihurca Almonte-Montes de Oca, Rosa N. Cueto, Melissa Rodríguez-Israel, Alicia G. Torterolo-Herrera, Vicente Villacreses, Gustavo Restrepo
Institutions: Instituto do Coração - HCFMUSP, Centro Médico ABC, Instituto Nacional de Cardiología, Universidad Abierta Interamericana, Hospital Italiano La Plata, Universidad Pontificia Bolivariana, Hospital Universitario de San Vicente Fundación, University of Ottawa, Ottawa Heart Institute, Hospital Universitario Austral, Hospital del Salvador, Institute of Cardiology, Instituto Cardiovascular de Buenos Aires, Mayo Clinic, Fundación Valle del Lili, University Health Network, Cedars-Sinai Medical Center, University of California, Los Angeles, University of California System, Hospital Fernández, Universidade Federal do Rio Grande do Sul, Hospital Dipreca, Mutualista Hospital Evangélico, Pontificia Universidad Católica de Chile, IPS Central, Hospital Italiano de Buenos Aires, Hospital Doctor Hernán Henríquez Aravena, Cleveland Clinic, Hospital Punta Pacifica, Hospital de Clínicas
Language: Spanish
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7223287757