Correlation between the Prevalence of Colorectal Polyps in Patients with and without a Family History of Colorectal Cancer
Year: 2026
Type: article
Study design: Observational Study
Abstract: Colorectal cancer (CRC) ranks third among the most frequently diagnosed cancers in Brazil and worldwide. To evaluate the prevalence of colorectal polyps in asymptomatic patients undergoing screening colonoscopy, comparing individuals with and without a first-degree family history of CRC. The present was a cross-sectional, analytical, retrospective, and comparative study based on the review of electronic medical records of asymptomatic patients aged ≥ 45 years who underwent screening colonoscopy between January 2019 and April 2024 at the Endoscopy Unit of the University Hospital of Universidade Federal do Maranhão. Patients were divided into two groups: group I (GI) and group II (GII). A total of 1,497 patients were included, with a mean age of 54 ± 12 years, and a predominance of females (57.5%). Group I comprised 1,367 patients, while GII included 130 patients. Colorectal polyps were identified in 550 patients (36.7%), corresponding to 506 patients in GI (37.0%) and 44 patients in GII (33.8%), with no statistically significant difference between the groups (p > 0.05). Hyperplastic polyps were the most frequent subtype in both groups, followed by adenomatous and inflammatory polyps, with no hamartomatous polyps identified. No statistically significant differences were observed between the groups regarding adenoma prevalence, histological subtypes, polyp location, or sex distribution (p > 0.05). No statistically significant association was observed between the presence of colorectal polyps and a first-degree family history of CRC, nor with sex, anatomical location, or histological subtype of the polyps.
Source: Journal of Coloproctology
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7223391641