Gestione delle terapie antineoplastiche orali nei centri ematologici afferenti alla fondazione italiana linfomi: risultati di una survey nazionale sul ruolo infermieristico e sul monitoraggio dell’aderenza farmacologica
Year: 2026
Type: article
Study design: Observational Study
Abstract: BACKGROUND: The increasing use of oral antineoplastic therapies in oncohematology has significantly changed traditional care models, shifting treatment management to patients in the home setting. Low medication adherence is associated with reduced clinical effectiveness, increased toxicity, and poorer health outcomes. In this context, nurses play a key role in patient education, adherence monitoring, and ongoing support. AIM: To describe how oral antineoplastic therapies are managed in Italian hematology centers, focusing on service organization, healthcare professionals’ involvement, and the use of tools for monitoring medication adherence. METHODS: A descriptive cross-sectional survey was conducted among hematology centers affiliated with the Italian Lymphoma Foundation. Data were collected using a 15-item ad hoc questionnaire developed on the basis of a literature review and the study objectives. Responses were analyzed using descriptive statistics RESULTS: A total of 31 responses were collected (response rate 18%), of which 28 were analyzed. In 89.3% of centers, no dedicated nurse-led clinic or nursing role for oral therapy management was reported. Patient education and adherence monitoring were mainly physician-led and largely unstructured. In 71.4% of centers, no standardized tools were used to assess medication adherence. CONCLUSIONS: The findings highlight a heterogeneous and poorly structured management of medication adherence. Strengthening the nursing role, implementing structured educational interventions, and adopting validated assessment tools may improve adherence, treatment safety, and clinical outcomes.
Source: Dissertation Nursing
DOI: 10.54103/dn/30640
Language: English
Subfield: Family Practice
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7223570268