Work

Waste-to-nanomedicine: scalable production of apple pomace nanovesicle-enriched fractions as nanocarriers for hydrophobic bioactives at the intestinal epithelial interface

Year: 2026

Type: article

Abstract: Apple pomace nanovesicles, isolated by tangential flow filtration and loaded with ursolic acid via sonication, improved extracellular retention and limited cell association vs free drug in Caco-2 Transwell® model, supporting local intestinal delivery.

Source: Sustainable Food Technology

DOI: 10.1039/d6fb00278a

Authors: Edoardo Bertania, Angelo Modena, Elia Bari, Erika Del Grosso, Simona Turi, Rossana Rossi, Saleh Hamed, Yassine Jaouhari, Fabiano Travaglia, Guillaume Gilliard, Melissa Ann Graewert, Claudia Moscheni, Valeria Rondelli, Maria Luisa Torre, Anastasiia Murmiliuk, Dario Di Silvestre

Institutions: Università degli Studi del Piemonte Orientale “Amedeo Avogadro”, University of Padua, Institute of Biomedical Technologies, National Research Council, University of Milan, European Molecular Biology Laboratory, European Molecular Biology Laboratory

Language: English

Topic: Proteins in Food Systems

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDGs: Responsible consumption and production, Good health and well-being

Open Access status: diamond

Funders: Compagnia di San Paolo, Università degli Studi di Milano, European Molecular Biology Laboratory, European Commission, European Synchrotron Radiation Facility, Forschungszentrum Jülich, Deutsches Elektronen-Synchrotron, NextGenerationEU

Awards: G2157353503, G231133531, G2370974534, G5869929732, G972786147

OpenAlex ID: W7223651986

FWCI:

Cites: 96

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Related to: 10