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Nose–Brain Axis: An Emerging Link among Nasal Inflammation, Neuropsychiatric Disorders, and Brain-targeted Therapy

Year: 2026

Type: article

Abstract: AnAtomIcAl BAsIs o f t h e nose-BrAIn AxIsThe nasal cavity consists of vestibular, respiratory, and olfactory regions.The olfactory epithelium contains olfactory sensory neurons whose axons pass through the cribriform plate and reach the olfactory bulb, providing one of the shortest anatomical connections between the external environment and the brain.1,3 The trigeminal nerve provides another important pathway, with its branches extensively innervating the nasal mucosa and establishing connections with the brainstem and other central structures.2,

Source: Delhi Psychiatry Journal

DOI: 10.5005/dpj-11077-0021

Authors: Bani Rai, Nirmaljit Kaur, Shalini Malhotra, Manjeet Singh Bhatia

Institutions: Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, Jamia Hamdard

Language: English

Topic: Olfactory and Sensory Function Studies

Subfield: Sensory Systems

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W7223687595

FWCI:

Cites: 11

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Related to: 10