A multi-pathway kinetic framework to correct real-time-storage extrapolation biases in biopharmaceuticals: code and processed data
Year: 2026
Type: software
Abstract: Code and processed data for the article "A multi-pathway kinetic framework to correct real-time-storage extrapolation biases in biopharmaceuticals" (Özdemir et al., mAbs, manuscript 268868859, revised version). The archive contains Supplementary Materials S1–S6: S1, the multi-pathway kinetic framework with statements and proofs (PDF and LaTeX source); S2, a worked demonstration (Jupyter notebook); S3, the Monte-Carlo validation; S4, checks on digitized published series; S5, the code for Figures 1–8; S6, the error bars, bootstrap intervals and prediction intervals. It also contains the processed stability data (cqa_all.json) and the output of S6 (uncertainty.json). To reproduce the results, use Python 3.12 with the packages listed in requirements.txt, and run S6 before S5. Random seeds are fixed. See README.md in the archive for details.
Institutions: Marmara University, Istanbul Technical University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7223703312