Work

Cutaneous mucormycosis at the onset of type 1 diabetes in two pediatric patients

Year: 2026

Type: article

Abstract: Type 1 diabetes (T1D) can present with diverse clinical manifestations, including opportunistic infections secondary to hyperglycemia-induced immunosuppression. While bacterial and viral infections (particularly COVID-19) have been well-documented as presenting features of new-onset T1D, mold infections as the initial manifestation remain rare. Mucormycosis, an aggressive angioinvasive fungal infection with high morbidity and mortality, typically occurs in patients who are severely immunocompromised. Here we present two pediatric cases of cutaneous mucormycosis arising at the onset of previously undiagnosed T1D, demonstrating that even newly established hyperglycemia is sufficient to create the conditions necessary for Mucorales invasion at sites of skin injury.

Source: IDCases

DOI: 10.1016/j.idcr.2026.e02816