Laparoscopic right hemicolectomy for colon cancer: is functional end‑to‑end anastomosis superior to end‑to‑side anastomosis? A meta‑analysis
Year: 2026
Type: review
Study designs: Systematic Review, Meta-Analysis
Abstract: INTRODUCTION: Right-sided colon cancer (CC) represents a substantial proportion of colorectal malignancies, and laparoscopic right hemicolectomy has become the established surgical standard of care. However, consensus on the optimal anastomotic configuration-end-to-side vs functional end-to-end-remains lacking in current clinical practice. AIM: This study aimed to compare end-to-side anastomosis (ESA) with functional end-to-end anastomosis (FEEA) in laparoscopic right hemicolectomy for CC involving extracorporeal anastomosis, thereby providing evidence-based guidance for selecting the optimal anastomotic technique. MATERIALS AND METHODS: We systematically searched PubMed, Web of Science, the Cochrane Library, and Embase for studies comparing ESA with FEEA in laparoscopic right hemicolectomy for CC involving extracorporeal anastomosis. The search included publications up to January 2026 with no language restrictions. Eligible studies were selected based on the population, intervention, comparison, outcome, and study design framework. RESULTS: <0.001). No significant differences were observed between ESA and FEEA in length of hospital stay, time to first flatus, overall postoperative complications, anastomotic leakage, postoperative bleeding, or surgical site infection. CONCLUSIONS: In laparoscopic right hemicolectomy for CC involving extracorporeal anastomosis, ESA is associated with a lower incidence of ileus than FEEA.
Authors: Feng Chen, Jianxiang Wu, Jianchun Zheng
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,480
OpenAlex ID: W7223857281