Work

Disruption of the N-terminal domain in a STAT3 hyper-IgE syndrome variant causes disease by sequestering STAT3 in the cytoplasm

Year: 2026

Type: article

Source: Science Signaling

DOI: 10.1126/scisignal.aeg5302

Authors: Joseph Mackie, Dan Suan, David B. Langley, Danielle T. Avery, Geetha Rao, Alexandra F. Freeman, Paul E. Gray, Francis Gracias Flor, Satoshi Okada, Daniel Christ, David R. Croucher, Antoine Guerin, Cindy S. Ma, Stuart G. Tangye

Institutions: Garvan Institute of Medical Research, UNSW Sydney, National Institute of Allergy and Infectious Diseases, Sydney Children's Hospital, Hiroshima University

Language: English

Topic: Immunodeficiency and Autoimmune Disorders

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7223865214

FWCI:

Cites: 70

Cited by:

Related to: 10