RBM15/IGF2BP1-mediated m6A methylation of AKR1B10 promotes the progression of cervical squamous cell carcinoma.
Year: 2026
Type: article
Abstract: OBJECTIVES: A) modification and has been shown to be associated with the initiation and progression of various malignancies. This study aims to investigate the biological function and underlying mechanism by which RBM15 promotes the progression of cervical squamous cell carcinoma (CSCC) through in vitro and in vivo experiments. METHODS: mRNA stability were analyzed. RESULTS: >0.05). CONCLUSIONS: A modification promotes CSCC progression through the IGF2BP1-AKR1B10 axis. RBM15 may serve as a potential biomarker for predicting outcomes in patients with CSCC.
Source: PubMed Central
Language: English
Topic: RNA modifications and cancer
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7223947966